TC10 is a small GTPase found in lipid raft microdomains of adipocytes.The protein undergoes activation in response to insulin, and plays a key role in the regulation of glucose uptake by the hormone.TC10 requires high concentrations of magnesium in order to stabilize guanine nucleotide binding.Kinetic analysis of this process revealed that magnesiu
Fundamental life science and pharmaceutical research are continually striving to provide physiologically relevant context for their biological studies.Zebrafish present an opportunity for high-content screening (HCS) to bring a true in vivo model system to screening studies.Zebrafish embryos little girls sweatpants and young larvae are an economica
Atrial switch procedures such as the Mustard operation were previously popular for the complete transposition of the great arteries (i.e.dextro-transposition of the great arteries [d-TGA]).Patients with d-TGA who underwent atrial switch procedures approximately three decades ago have now entered adulthood.A female patient in her 30s with d-TGA had
Purpose.The use of anti-friction traction motor support bearings (TMSB) instead of plain friction traction motor support bearings is a priority direction of locomotive development both for newly constructed locomotives and for those in operation.The solution of the set tasks for introduction of wheel-motor blocks (WMB) with anti-friction bearings d